Chloramphenicol 20% W.S.P
Each 100 gm contain 20 gm chloramphenicol.
- Chloramphenicol is abroad spectrum antibiotic active against Gm+ve, Gm-ve bacteria, spirochaetes and rickettsiae.
- After administration within 2 hrs. blood levels of it is increased, which are mintained for at least 24 hrs.
Gastroenteritis, pneumoina, polyarthritis, metritis, infections of urinary tract and infectious diarrhea.
1- Hypersensitivity to chloramphenicol, in newborns, liver dysfunction.
2- Not administered during gestation and lactation period.
3- Not used in cases of mastitis.
Long term treatment may cause reversible depression of hematopieosis, intestinal disturbances and seldom an irreversable bone marrow toxicity resulting in fatal aplastic anemia.
1- Chloramphenicol can inhibit the hepatic metabolism of several drugs including phenobarbital and pentobarbital.
2- Possible antagonism with bactericide antibiotic such as Penicillin, Amino glycosides and Cephalosporines.
3- Rifampin may decrease serum Chloramphenicol level.
40 - 80 mg./kgm. body weight.
1- Meat 3 weeks.
2- Milk 3 days.
Packing: 200 gm, 500 gm
Cool dry place away from direct sunlight.
1- Stability 2-3 years.
2- Medicated water should be supplied within 24 hrs.